STREAMLINE Kick-off Meeting took place in the Hotel Putnik Inn, Belgrade, Republic of Serbia on July 7th, 2022. Meeting organizers were academician Milena Stevanovic (IMGGE), Prof. Adrian Harwood (CU), Prof. David Linden (UM), Dr. Spyros Petrakis (CERTH) and Dr. Danijela Drakulic (IMGGE). This hybrid event gathered all participants and associates of STREAMLINE with 25 in-person attendees and 16 remote meeting participants. On this occasion, the official beginning of the Project was declared. The event was also an opportunity to represent work packages and to set up the General Assembly and the Ethics Advisory Board. Kick-off Meeting was also a chance to discuss the action plan for the next period, as well as to debate current topics and challenges in the field of Neurodevelopmental Disorders (NDDs) from scientific, medical, ethical and patient points of view.